Important Of Sight For The Purpose Of Survival Biology Essay

Important Of Sight For The Purpose Of Survival Biology Essay The importance of sight has been one of the most taken for granted systems in the human body. Sight, like the other four senses, plays an important role in the survival of an individual. In primitive humans, a loss of vision would make predator avoidance and food gathering difficult. Hence, there is an evolutionary pressure to maintain vision even when the eye sustains injury. While the eye is highly developed, certain post trauma mechanisms have evolved in such a way that our visual axis will not be altered, which would normally lead to instant blindness. Damage done to any normal part of the body usually leads to some sort of immunological response, including inflammation caused by the lymphocytes. Due to the physiology of the ocular system of mammals, the cornea cannot sustain inflammation, which can lead to the changing of the visual axis, thus leading to blindness. In primitive man, blindness could potentially lead to the individuals death. In order to prevent this, certain immu nological responses are suppressed in the cornea, allowing vision to remain. Keratitis is the clinical diagnosis of inflammation of the cornea, which if left untreated, can lead to blindness of the patient. This paper will use the Darwinian Medical approach and the Adaptationist Program to discuss the implications of the suppressed immune response in development and treatment of keratitis and the various microbial and mechanical causes thereof. In order to understand topics covered in this paper, a basic explanation of structures of the eye, their functions, as well as mechanisms and associated pathogens must be explained. Keep in mind, what will be mentioned is a buildup all to save the visual axis. The main anatomical focuses of the eye for this paper are the cornea and the anterior chamber. Concluding this will be a brief description of Darwinian Medicine and the Adaptationist Program. The cornea has two main functions and is composed of five layers. It acts as a protective membrane for the eye. The five layers consist of the following, in order from anterior to posterior, an external stratified squamous epithelium, an anterior limiting membrane (Bowmans membrane, the basement membrane o the stratified epithelium), the stroma, a posterior limiting membrane (Descemets membrane, the basement membrane of the endothelium), and an inner simple squamous endothelium. 1. The main functions of the cornea are to act as a protective membrane as well as to be the transparent window that allows light to enter through the eye to the retina. This unique transparency is due to the uniformity of the cell structure, being devoid of blood vessels, and being in a constant state of dehydration. If the epithelium is damaged, there is only a temporary regional build up of watery fluids in the stroma. However, if trauma is severe enough to expose any corneal layer below the epithelium, the cornea then becomes susceptible to infection of a variety of pathogens. These include, but are not limited to the following: bacteria, fungus, amoeba, and herpes virus.2. Without medical intervention, the basic stages of corneal infections are as followed: trauma, entrance of pathogen, inflammation of the cornea, ulceration, loss of vision, and even possibly loss of the eye. Located between the endothelium of the cornea and the iris, is a fluid filled cavity called the anterior chamber. The anterior chamber of the eyeball is filled with thick liquid-like substance called the aqueous humor. Its primary function is to maintain a normal intraocular pressure as well as provide nutrition for the tissues with no veins attached to them. In the anterior chamber, specifically the aqueous humor, there is a presence of a wide variety of immunoglobulins, as well as a wide variety of immunosuppressive substances such as transforming-growth-factor- Ã‚ ¢ and macrophage-migration-inhibitory-factor. A theory deemed Anterior-chamber associated immune deviation will be discussed later in this paper alongside with ocular-immune privilege. 3. The Darwinian Medical approach looks at both proximate, biological causes, as well as the ultimate, evolutionary causes to explain a disease or an immune function such as a fever. Ultimate causes are usually more complex in their explanations, which include defense, infection, novel environment, genes, design compromise, and evolutionary legacy all of which are evolutionary driven by four forces: natural selection, mutation, gene flow, and genetic drift. Evolutionary causes of an excessive and uncontrolled defense mechanism can affect the risk of the disease. Other risk factors include losing the evolutionary arms race, the preservation of an allele that is harmful, and the result of evolutionary constraints. While keratitis is classified as an infliction, it is actually an immune response related to the infiltration of a pathogen in the cornea. As stated above, keratitis is the inflammation of the cornea. Symptoms include mild to sever pain in the eye, redness of the eye, opaque cornea, photosensitivity, and tearing. Clinical diagnosis of keratitis is done through examination using a slit lamp and proper illumination, Fluorescein stain to detect superficial corneal lesions, and laboratory examinations of corneal scrapings to detect pathogens. 2. Inflammation caused by pathogens is potentially harmful leading up to corneal ulceration, loss of the visual axis, and potentially blindness. The inflammation however is the lesser of two evils, for without having this immune response, the sight of the infected would be doomed to blindness. While this is true, an eyes last-ditch effort to remove the pathogen leads to over-inflammation and ulceration of the cornea. At that point, unless a corneal transplant is done alongside with medicine to kill the pathogen, the eye has given up and the host goes blind. To regulate inflammation and prevent ulceration, it has been hypothesized that there is design compromise called ocular immune privilege in the eye that regulates inflammation up to a certain point. This will be discussed later. The epidemiological qualities of keratitis fluctuate etiologically as well as geographically. Keratitis has risen in both developing countries as well as modernized countries, afflicting people worldwide with no restrictions based on economic status. Thousands of patients each year are diagnosed with some form of pathogenic keratitis, having each pathogen found in particular environments found worldwide. Anyone involved in agriculture is usually at risk for fungal keratitis. Anyone wearing contacts are at an even higher risk for not only fungal keratitis, but also bacterial and amoeba induced keratitis. However, anyone who has any sort of ocular trauma led to lesions in the cornea is susceptible to any form of microbial keratitis. 2. The evolutionary legacy of ocular immune privilege is the result of evolutionary constraints and design compromises. In order to preserve the function of the eye, inflammation is regulated by the hosts adaptive immunity, specifically called ocular immune privilege. Immune privilege has been recognized in only three organs; the testes and ovaries, the brain, and the eye. 5. Coincidentally, these are some of the most important organs in the body related to survival and spreading of ones genome. Adaptive immunity is compromised of lymphocytes that throughout life generate unique receptor molecules that recognize with extraordinary specificity molecules expressed by invading pathogens. 3. (pg 11). It is important to understand this concept to elucidate the mechanisms of ocular immune privilege and ACAID. Ocular Immune privilege was first described about 130 years ago. However, its importance was not recognized until the early 1940s by P.B. Medawar and his colleagues. During the 1970s, it was discovered that ocular immune privilege was caused by anatomical, physiological, and immunoregulatory processes, which prevent the introduction and expression of immune-mediated inflammation. Many ophthalmological researchers agree that ocular immune privilege is an adaptation for reducing immune-mediated injury to ocular cells that have limited or no capacity for regeneration.6. The three major mechanisms of ocular immune privilege are as followed: (1) there are anatomical, cellular, and molecular barriers in the eye; (2) eye-derived immunological tolerance (ACAID); and (3) immune suppressive microenvironment in the eye. 5. Anterior chamber-associated immune deviation, or ACAID, is directly related to the ocular immune privilege theory. ACAID is characterized by impaired antigen-specific delayed -type hypersensitivity and reduced production of complement fixing antibodies. 3. It is an observable fact that allows the antibody response but not the cellular responses mentioned above. 5. The discovery happened when there was a prolonged survival of genetically different transplanted tissue survived in the anterior chamber of the eye. The failure of the immune system to bring forth an immunological response composes the characteristics of immune privilege. This is the reason why corneal transplants are one of the most successful, and least rejected tissue transplant clinically practices. Most tissue transplants are rejected due to inflammation however, the cornea has a weaker immune response caused by low antigenicity, the difference between corneal versus other tissue grafts. 7. The mechanisms of ACAID involve both the eye and the spleen. Transforming Growth factor TGF- Ã‚ ¢2 and thrombospondind TSP-1 located in the anterior chamber are involved in the initiation of mediation of ACAID. Through this, there is an attraction of regionally located natural killer T cells, which bind to CDQd molecules to present the antigens. When these cells come in contact with marginal zone B cells, clusters are formed which then differentiate into ACAID-inducing regulatory T cells. 5. A recent discovery made by Molly E. Skelsy and colleagues, concluded that  Ã‚ Ã‚ ¤ T cells are needed for ocular immune privilege and corneal graft survival. The study used mice treated with anti- Ã‚ Ã‚ ¤ Ab failed to develop ACAID concluding the injection of spleen cells. It was concluded that these T cells were required for the creation of regulatory T cells. By blocking the creation of  Ã‚ Ã‚ ¤ T cells, Skelsey showed that there was a profound increase in corneal transplant reje ctions. 8. Another recent discovery was that thymocytes, cells created by thymus that generate into T lymphocytes, are also necessary for the induction of ACAID. Thus the sustainment of immune privilege in the eye is done through the mutual aid of various cells from organs other than the eye itself. 5. The adaptive immunity is expressed in the form of humoral immunity mediated by antibodies produced by B lympocytes, and in the form of cellular immunity mediated by T lymphocytes. 3. (pg 15) Clearly, ocular immune privilege isnt something that just arose out of nowhere. It has been an evolutionary legacy, because whatever beneficial implications it had, leading up to ACAID, must have been immediately beneficial for it to exist throughout the evolution of many mammals such as humans and even mice. In 2008, Xiaoyong Yuan and colleagues did a study to compare the gene expression patterns in uninfected and fungus-infected mouse corneas at the onset of Candida albicans fungal keratitis. Candida ablican related corneal infections cause an inflammatory response, which has been known to permanently impair vision in half of all eyes affected, including those with therapy. Infected eyes were observed and corneal transcriptomes were categorized to suggest pathways contributing to corneal inflammation during Candida related keratitis. Through the use of gene microarray, the hosts gene expression during the early stages of this keratitis was also observed in mouse models. RNA isolated from the corneas one day after inoculation were used for reverse transcription of the RNA which would then be used in a quantitative real-time RT-PCR to multiply the amount of DNA created. Gene expression levels were calculated for both the experimental group and the control group. When comparing the two groups, a total of 45,102 genes were detected. Of those genes, 3,977, roughly 8.82% of the infected corneas were significantly regulated. Of those genes, 1987 were upregulated and 1,990 were down-regulated. A total of 3.71% were differentially expressed, 1,075 being upregulated and the other 597 being down-regulated. Specifically, there were 30 different genes being upreglated more than 100 fold. These genes were categorized as chemokines, metalloproteinases, interleukin cytokines, leukocyte chemotaxis and surface molecules, Ig recept ors, Neuro-hormone mediatiors and many others. Simply stated, these gene expressions suggest that microbial keratitis involves the synchrony of various host processes that affect inflammatory and immune responses, intercellular communication, and cellular metabolism in other words, ocular immune privilege and ACAID. 9. Keratitis is a microbial infliction occurring globally. Bacteria, parasites, virus, and fungus cause the four main microbial causes for infection. These microbes are currently winning the at arms race due to an increased virulence and re-infection after treatment. At the same time, because there have been changes in mans history, various novel environments have been associated with the etiology of all these infections. Looking at a study in a referral centre in South India from September 1999 through August 2002, MJ Bharathi and colleagues observed and calculated the statistics of keratitis in that referral centre. Of 3183 corneal scrapings evaluated, 1095(34.4%) were fungal related, 1043(32.77%) were bacterial related, 33(1.04%) were acanthamoeba related and 76(2.39) were both bacterial and fungal related. Of the 1043 bacterial related infections, the predominant isolated bacteria were Streptococcus. Males were 56.76% of cases and females were 43.24%, thus showing that sex doesnt af fect the infiltration rate. In the study, 60.2% patients were over the age of 50 were affected significantly more than patients under the age of 50. Roughly 16.97% of corneal injuries were due to soil/sand, compared to the 11.03% caused by other materials, showing a statistical significance between the two. Seasons also affected the rate of infections showing a lower incidence of bacterial keratitis from the months of June to September. 10. The epidemiology of bacterial keratitis varies based on geography. One could acquire keratitis from numerous gram-positive or gram-negative bacteria, such as Serratia, Pseudomonas, and Staphylococcus. Once the bacteria has touched base with the cornea, it colonizes the hosts cells by using adhesins at the surface of the epithelium. The adherence of these three bacteria to the corneal epithelium is significantly higher than any other bacteria, which explains their high frequency of isolation. Several bacteria have also displayed adhesins on pili and nonfimbriae structures to recognize carbohydrates on host cells. Recently, there have been emerging cases of resistance among pathogens, requiring the emersion of a stronger antibacterial to eradicate it. 11. The advent of contact lenses has created a novel environment for the infiltration of many bacterial pathogens. In the United States, there are approximately 25,000 cases of infectious keratitis annually. There are roughly 2-4 infections per 10,000 soft contact lenses users, and 10-20 infections per 10,000 extended-wear contact lenses users. 14. A study done by T. Bourcier and colleagues has identified predisposing factors of bacterial keratitis. After analyzing 300 cases, contacts were the main risk factor, occurring in 50.3% of the study group, with 83% of bacteria being gram positive, and 17% being gram negative. 12. Another study of a case report done by Konstantinos Tsaousis and colleagues concluded that the incidence of bacterial keratitis can be reduced by maintaining high standards of lens hygiene and following the recommended guidelines to safely wearing contacts. 13. In the past, fungal keratitis has been a major ophthalmological problem in the tropical regions of the world. 16. Of all of the fungus related to keratitis, there are two classifications of infiltrates yeast and filamentous fungi. The three main isolates of fungus in fungal keratitis are Aspergillus, Fusarium, and Candida. While the most common of isolate reported has been Aspergillus, ranging from 27-64%, Fusarium comes to a close second (6-32%). Like bacterial keratitis, contact lenses wearers are at a higher risk of fungal infection. In recent news, on March 8, 2006, the CDC began an investigation of the use of Bausch Lomb ReNu contact lens solution. The solution had been related to a series of 130 confirmed cases of Fusarium Keratitis, which resulted in 37 corneal transplant surgeries. Most fungal related incidences however are usually related to agriculture. Since fungus are found in soil and on plants, the probability of infection after ocular trauma increases if one is tendi ng to their crops. Once the fungus accesses the corneal stroma, they multiply and cause tissue necrosis leading to the onset of keratitis and the loss of stromal opacity. 15. Acanthamoeba related keratitis is usually derived from standing water or mud, with an increased risk in contact users. Incidence per million contact lens users includes 333 in Hong Kong, 1 in USA and 149 in Scotland 14. The abnormally high incidence in Scotland is due to the fact that there are many water towers, holding standing water, a novel environment for the acanthamoeba. Survival in the wild is not only based on ones ability to escape a predator, but also ones ability to detect the predator. The up keeping the visual axis is one of the most important abilities of the eyes immune abilities for without sight, many mammals would be at disadvantage. Keratitis, the inflammation of the cornea, has probably been around since the dawn of man, and more specifically, the dawn of agriculture. If injury to the eye were to be sustained, the cornea would become inflamed. Normally, corneal cellular layers would be impaired, leading to a loss of the visual axis. However, it has been observed that there is a key mechanism that has developed over time in order to save ones sight. There is an ocular immune privilege, considered to be an evolutionary legacy as well as a design compromise, in the anterior chamber of the eye, which limits certain immune functions to prevent the loss of vision. The microbial pathogens cause these infections ranges from bacterial, to funga l, viral, and amoebic have been detected around the world, causing countless keratitis infections. Novel environments, such as contact lenses, have created the perfect environment for these pathogens to culture on especially if proper care protocols havent been taken. While most of these infections are treatable, in the long term, the microbes are winning the at arms race. With increase resistance to anti-bacterials/fungals, pathogens will only become more virulent. From an epidemiological standpoint, microbial keratitis poses a serious threat for future infected patients, occurring world-wide. Mescher, Anthony L. PhD. (2010). Junqueiras Basic Histology: Text Atlas, 12e. In accessmedicine. Retrieved 10/1/10, from http://www.accessmedicine.com/content.aspx?aID=6183284searchStr=cornea#6183284. Biswell, Roderick MD. (2008). Vaughan Asburys General Ophthalmology, 17e. In accessmedicine. Retrieved 10/1/10, from http://www.accessmedicine.com/content.aspx?aID=3090961searchStr=cornea#3090961. Streilein, J.W. et al, 1999: Immune Response and the Eye. Karger, Switzerland Nesse, R. M. and Williams, G.C. 1994: p.x, Why We Get Sick. The New Science of Darwinian Medicine, Vintage, New York Junko Hori. (July 16, 2008). Mechanisms of immune privilege in the anterior segment of the eye: what we learn from corneal transplantation. In PubMed Central Journal List. Retrieved 10/1/10, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802514/?tool=pubmed. Niederkorn, Jerry Y. PhD, Streilein, Joan. PhD. (January 2010). History and Physiology of Immune Privilege. In Informa healthcare. Retrieved 10/1/10, from http://informahealthcare.com/doi/abs/10.3109/09273940903564766. Junko Hori, MD, PhD1, Vega, Jose L. MD, PhD2, Sharmila Masli, PhD3. (October 2010). Review of Ocular Immune Privilege in the Year 2010: Modifying the Immune Privilege of the Eye. In Informa healthcare. Retrieved 10/1/10, from http://informahealthcare.com/doi/abs/10.3109/09273948.2010.512696. Skelsey, Molly E., Mellon, Jessamee., Niederkorn, Jerry Y. . (2001). {{gamma}}{{delta}}T Cells Are Needed for Ocular Immune Privilege and Corneal Graft Survival. In The Journal of Immunology. Retrieved 10/1/10, from http://www.jimmunol.org/cgi/reprint/166/7/4327. Xiaoyong Yuan, Mitchell, Bradley M., and Wilhelmus, Kirk R. (September 18, 2008). Gene profiling and signaling pathways of Candida albicans keratitis. In PubMed Central Journal List. Retrieved 10/1/10, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562425/. Bharathi MJ, Ramakrishnan R, Vasu S, Meenakshi R, Shivkumar C, Palaniappan R. Epidemiology of bacterial keratitis in a referral centre in South India. Indian J Med Microbiol 2003;21:239-45 OBrien, T P . (February 2003). Management of bacterial keratitis: beyond exorcism towards consideration of organism and host factors. In Cambridge Ophthalmological Symposium. Retrieved 10/1/10, from http://www.nature.com/eye/journal/v17/n8/full/6700635a.html. Bourcier T, Thomas F, Borderie V, Chaumeil C, Laroche L . (January 10, 2003). Bacterial keratitis: predisposing factors, clinical and microbiological review of 300 cases. In PubMed Central Journal List. Retrieved 10/1/10, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1771775/?tool=pubmed. Tsaousis K.T., Sakkias G., Kozeis N., Tahiaos P. . (July 19, 2010). A Management Dilemma: Infectious Keratitis Associated with Soft Contact Lens Use and Dubious Treatment Compliance. In PubMed Central Journal List. Retrieved 10/1/10, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2935133/?tool=pubmed. Trevor John Mills, MD, MPH. (December 2, 2009). Corneal Ulceration and Ulcerative Keratitis. In Emedicine from WebMD. Retrieved 10/1/10, from http://emedicine.medscape.com/article/798100-overview. Daljit Singh, MBBS, MS, DSc. (June 12, 2008). Keratitis, Fungal. In Emedicine from WebMD. Retrieved 10/1/10, from http://emedicine.medscape.com/article/1194167-overview. Gopinathan, Usha Ph.D et al . (August 2002). The Epidemiological Features and Laboratory Results of Fungal Keratitis: A 10-Year Review at a Referral Eye Care Center in South India. In Cornea, The Journal of Cornea and External Disease. Retrieved 10/1/10, from http://journals.lww.com/corneajrnl/Abstract/2002/08000/The_Epidemiological_Features_and_Laboratory.4.aspx.

Health Campaign Essay

Part I of this paper examined childhood obesity as a public health issues that faces the state of Texas. Further, the paper dwelt on the importance of addressing this public health issues because it has an impact on the lives of the children at the community, state, and national levels. Moreover, the paper also identified the models and systems that have found use in the determination and of childhood obesity, along with the associated vital statistics involved, and management care. The research paper revealed how prevalence in childhood obesity in the state of Texas increased from 5. % to 10. 9% for children between the ages of 7 to 12 between 1970 and 1995. In an effort to address this public health issues, community organizations, the state of Texas as well as the federal government have also played a pivotal role in taking initiatives to help address this epidemic. At the community level, local agencies including health clinics and community centers have all been actively involved in the fight against childhood obesity. Parents, schools, and the community are all charged with the responsibility of creating awareness about the childhood obesity epidemic. State agencies that are dealing with obesity in Texas include the Texas Obesity Research Center and the Health and Human Commission. At the national level, The Center for Disease Control and Prevention and the National Childhood Obesity Foundation has been instrumental in the fight against childhood obesity. At the national level, the Center for Disease Control (CDC) has provided two yardsticks with which to divide children above the age of 2 years who are also overweight. In the first category, those children who are above the 85th quartile of obesity are often identified as being within the at-risk level. In the second category, those who are above the 95th quartile are categorized as being in the severe level. Perhaps we need to ponder on the question of why there are more overweight children in the state of Texas in comparison with the national average. The main reason behind this could be the fact that compared with the larger United States, Texas is by and large more ethnically diverse. African Americans and Hispanic children have been seen to present a higher prevalence of obesity in comparison with the other children, such as the Whites or Caucasians. Although the number of African Americans in the population of Texas is a reflection of the national percentage (in this case, the African Americans in the Texas population are 11. 5% while at the national level, the figure is 12. 3%), however, there are more Hispanics in the state of Texas in comparison with the national average (that is, 32% vs. 12. 5%). Nearly 40% of the children in the various public schools in Texas are of Hispanic descent, with the White children and the African Americans accounting for a further 43% and 14% respectively. Target Population Accroding to the research findigns undertaken by the NHANES (National Health and Nutrition Examination Survey) between 2007 and 2008, 17 percent of children along with adolescents who were of the ages between 2 and 19 years were categorized as being obese. Further, the study revealed that obesity prevalence among this target group was also seen to rise between 1976 and 1980. Again, a similar trend was observed between 1999 and 2000 (CDC 2010). On the other hand, a survey undertaken among high school students in Texas indicated that nearly a third of them (28. 7 %) were either bese, or overweight ((Burns, Nyberg & Parker, 2007). In addition, the January 2009 state demographer of Texas indicates that by 2040, there shall be 15 million obese individuals in the state if at all no preventive measures are undertaken. This represents a threefold increase of the current population of obese individuals. Barclay (2010) contends that in 2007, the national prevalence rate of obesity among children in the US stood at 16. 4 %. What this appears to suggest is that the prevalence of obesity among children in the state of Texas is nearly double the national figure. Accordingly, a child in Texas is more likely to be obese that the average child in the United States. This could be attributed to the issue of race. For example, Texas has a higher percentage of African Americans and Hispanics than the national average. The two races have been shown to be more pre-disposed to obesity than any other race, and so the apparent variation in obesity rates in the state of Texas. The national infant mortality rate in the United States as of 2007 stood at 6. 3 deaths for every 1000 live births, according to statistics released by CDC (2007). On the other hand, in the same year, the infant mortality rates in the state of Texas stood at 6. 2 deaths for every 1000 live births (Texas Department of Health Services, 2007). There is the need for adopting sustainable intervention measures in as far as the issue of child obesity in the state of Texas at the community level if at all the prevalence rates of this epidemic are to reduce. One such intervention is the FFV (Fresh Fruit and Vegetable) Program. The aim of the FFVP is to ensure that school-age children have access to free vegetables and fruits all day long, while at school. The target group is therefore children of school-going age. They are normally encouraged to adopt healthy eating habits. In addition, the schools that takes part in the project avails a controlled setting in which the manipulation of the environment is possible. At the national level, the FFVP program is usually administered by the Food and Nutrition Service of the USDA. On the other hand, the Department of Agriculture in Texas is charged with the responsibility of administering this program at the state level (Jeffers, 2003). In Texas, the program administrator of the FFVP is responsible for managing and overseeing this program. The determination of the success of the FFVP program would be a reduction in plate waste amounts and increase in the consumption of vegetables and fruits. Intervention As a community-based response to the issue, including community-based planning, needs assessments, and selection of locally identified objectives, the community considered created a Get Out and Race in Racing campaign in order to increase physical activity in the community and respond the issue of obesity. There are economic factors and funding intervention strategies to address these issues. Each year the state spends in excess of $337 million on obesity-directly related diseases and conditions (Nevada State Health Division Bureau for Community Health, 2006). Campaigns will help the community members become aware of these costs and how these funds could be better used to promote health. Statewide partnerships with community and business members will be formed to seek ways to increase funds needed for the program. Funding interventions will include community, business, and school-held events to raise capital to include moneys and volunteers to assist with the program development and implementation, and ongoing evaluation. Schools will send home flyers asking for parent participation and contributions. Students will become involved in all efforts to raise conscious awareness of the problem, proposed solution, and needs for funding. Social marketing will have an important role in promoting public health related to the chosen issue of obesity. Social marketing will be needed to ensure parent and community awareness of the problems and proposed solutions. To assist with marketing agendas, meetings with parents and teachers will be held at the schools to ensure that parents are provided with information about health, obesity prevention, and physical exercise. These meetings will take place regularly to market the program while providing information. Efforts are designed to facilitate economic support as well as a commitment to adhering to the program (Elsawy & Higgins, 2010). At the institutional levels also, the school heads are called upon to ensure that they incorporate physical exercise in the school’s curricula as another strategy to facilitate in the reduction of obesity among children. In addition, churches and community centers in Texas could also be involved in the fight against obesity by way of forming educational programs aimed at creating awareness on the incidence, prevalence, and dangers of this epidemic, with the children and their parents as the target group. Lepard (2010) has underscored the need to make use of video games in school and at community centers with a view to helping reduce childhood obesity in the state of Texas. In addition, such educational programs also require incorporating behavioral change, such as exercise and the adoption of healthy eating habits (Cole et al, 2000). For purposes of sustainability of such programs as the FFVP, there is the need to ensure that a reliable source of funding has been identified. In this case, the USDA and the CDC are good examples of government agencies that are in support of such programs. Conclusion Obesity in Texas and United States is an important aspect of today’s health and it continues to rise. Awareness is being pushed through the state, local and national level to help fight this disease. Having the community, schools and family involved with ways to prevent and cure obesity can help fight the disease. Following the proper nutritional guide and exercise can have the start of a health life style.

The War Of The Vietnam War - 1311 Words

Soldiers in Battlefield It is a known fact that soldiers endure experiences that can only be felt by seeing through one’s own eyes. The Vietnam War was especially one of the wars that had a major impact on soldiers, as their lives became significantly more difficult and dangerous. The soldiers were young and thrown into war, not knowing who they were fighting. Tim O’Brien was one of the soldiers that was placed into Vietnam’s danger. O’Brien stated that he still carries â€Å"the memories or the ghosts of a place called Vietnam, the people of Vietnam, my fellow soldiers. More importantly [he carries] the weight of responsibility and a sense of abiding guilt. [He carries] joyful memories, too, friends [he] made and the conversations at foxholes†¦show more content†¦Throughout the war, â€Å"men [were] killed, dead human beings [were] heavy and awkward to carry, things smell[ed] different in Vietnam, soldiers [were] afraid and often brave, drill sergeants [were] boors, s ome men think the war [was] proper and just and others [did not] and most [did not] care.† (O’Brien, 135) After a war, many men suffer from depression and often re-see the pictures of their friends as they lost their lives. Although many men died, most Vietnam Veterans would say that they are proud that they served. Even though men were forced into Vietnam due to the draft and without a notice, they also felt the need to want to go into the war to protect their country. Young men, barely out of the age of being a boy, were pushed into Vietnam. Those young men had the terror of Vietnam â€Å"instead of happy childhoods.† (Smith, 1) The young soldiers were ripped out of their happy lives and were then living day-to-day not knowing when their last day would be. â€Å"Having come of age as the war in Vietnam became more an obligation than an option, particularly for a young Midwestern man from a solid family, regardless of education, O’Brien recalls doubting his initial vehement opposition to

How The Glass Booth Should Be Integrated Into The Museum

As a museum, our job is to create an experience for our visitors in order to leave an artistic impression in their heads. Many museums have attempted to create unique exhibitions such as period rooms and displays in order to amaze the crowds that travel through and make their experience a memorable one. Nowadays it is difficult to amaze a crowd that has so many resources at its disposable. The internet has made it possible to view any work of art with just the click of a button. It is for this reason that the Glass Booth should be integrated into the museum. With the financial support of the board, the purchase of three different stained glass pieces can be purchased to put together this unique booth so that the audience can experience the†¦show more content†¦This piece was created during the crusades and demonstrates an important message to those who would either go on the crusades or were contemplating converting to Christianity. The legend of the seven sleepers demonstra tes a protection from the lord for those who want to convert but are afraid of persecution. In the legend those who converted were noblemen which give an example to the common people as if to say that being Christian is indeed fashionable and done by the top of the hierarchy as well as the bottom. The second piece is a stained glass portrayal of a prophet. The piece is called Prophet. Created ca. 1390-1400, the context of the piece is unknown but at the time it was typical to see prophets in architectural settings. It is colorless glass with silver stain and vitreous gold paint. Created after the Valois branch took over the Capetian dynasty in 1328, this piece is significant in that it isn’t as colorful as stained glass mosaics that are typically shown in the cathedrals. The period in which this piece was made was significant because it was the last flowering of gothic art until the introduction of Italian Renaissance motifs in the 1450s by Jean Fouquets . The final piece of artwork is called the Adoration of the Magi, it is also stained glass and was created circa 1390. It is from the Schlosskapelle, Ebreichsdorf, Austria and is made from pot metal and colorless glass with silver stain